Figure 3

Subgroup comparisons: regulatory T cell levels at baseline in patients with melanoma before treatment with interferon-α 2b. Box plot subgroup comparisons of regulatory T cell (Treg) levels (%) at baseline in 22 patients with melanoma before treatment with interferon-α 2b (IFN-α 2b). (A) Adjuvant (ADJ) versus neoadjuvant (NEO) IFN-α 2b (P = not significant); (B) stage III versus stage IV (P = 0.082); (C) early recurrence (ER) versus no recurrence (NR) (P = 0.017); (D) surviving (ALV) versus deceased (DCD) (P = 0.021). Horizontal lines inside the boxes = median values; upper and lower boundaries of the boxes = first and third quartiles of the distribution; whiskers = mild outliers; open dots = outliers; and asterisks = extreme outliers.