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Table 5 Immunological parameters

From: Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions

Parameter Number of patients Before treatment After treatment Reference range P value Significance
T-cells (CD3)% of total T cells 113 79.91 (6.78) 77.67 (8.18) 61-85 0.001 In normal range but significantly decreased after treatment
Helper T-cell (Th cell/CD4) % of total T cells 114 48.84 (9.03) 45.44 (10.65) 28-58 <0.001 In normal range but significantly decreased after treatment
Ts cell (CD8)% of total T cells 114 25.38 (7.18) 26.89 (8.10) 19-48 0.005 In normal range but significantly increased after treatment
CD4/CD8 114 0.30 (0.20) 0.24 (0.23) -0.05-0.30 <0.001 In normal range but significantly decreased after treatment
IgG (g/L) 114 0.96 (0.12) 0.91 (0.14) 0.86-1.23 <0.001 In normal range but significantly decreased after treatment
IgA (g/L) 114 2.15 (0.79) 2.01 (0.72) 0.68-3.83 <0.001 In normal range but significantly decreased after treatment
IgM (g/L) 114 1.13 (0.62) 1.32 (0.72) 0.63-2.77 <0.001 In normal range but significantly increased after treatment
Complement C3 (g/L) 114 1.19 (0.23) 1.21 (0.25) 0.85-1.93 0.103 In normal range but no significant changes after treatment
Complement C4 (g/L) 114 -0.62 (0.17) -0.63 (-0.16) -0.92 - -0.44 0.283 In normal range but no significant changes after treatment