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Table 5 Immunological parameters

From: Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions

Parameter

Number of patients

Before treatment

After treatment

Reference range

P value

Significance

T-cells (CD3)% of total T cells

113

79.91 (6.78)

77.67 (8.18)

61-85

0.001

In normal range but significantly decreased after treatment

Helper T-cell (Th cell/CD4) % of total T cells

114

48.84 (9.03)

45.44 (10.65)

28-58

<0.001

In normal range but significantly decreased after treatment

Ts cell (CD8)% of total T cells

114

25.38 (7.18)

26.89 (8.10)

19-48

0.005

In normal range but significantly increased after treatment

CD4/CD8

114

0.30 (0.20)

0.24 (0.23)

-0.05-0.30

<0.001

In normal range but significantly decreased after treatment

IgG (g/L)

114

0.96 (0.12)

0.91 (0.14)

0.86-1.23

<0.001

In normal range but significantly decreased after treatment

IgA (g/L)

114

2.15 (0.79)

2.01 (0.72)

0.68-3.83

<0.001

In normal range but significantly decreased after treatment

IgM (g/L)

114

1.13 (0.62)

1.32 (0.72)

0.63-2.77

<0.001

In normal range but significantly increased after treatment

Complement C3 (g/L)

114

1.19 (0.23)

1.21 (0.25)

0.85-1.93

0.103

In normal range but no significant changes after treatment

Complement C4 (g/L)

114

-0.62 (0.17)

-0.63 (-0.16)

-0.92 - -0.44

0.283

In normal range but no significant changes after treatment