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Table 1 Immunohistochemical results of MMP-9, VEGF and PCNA

From: Low temperature of radiofrequency ablation at the target sites can facilitate rapid progression of residual hepatic VX2 carcinoma

 

Group

N

Expression density

No of cases

%

P

MMP-9

I

15

    
   

++

13

86.67

< 0.01

   

+

2

13.33

 
   

-

0

0.00

 
 

II

15

    
   

++

5

33.33

 
   

+

9

60.00

 
   

-

1

6.67

 
 

III

15

    
   

++

4

26.67

 
   

+

10

66.67

 
   

-

1

6.67

 
 

Control

15

    
   

++

0

0.00

 
   

+

7

46.67

 
   

-

8

53.33

 

VEGF

I

15

    
   

++

12

80.00

< 0.01

   

+

3

20.00

 
   

-

0

0.00

 
 

II

15

    
   

++

5

33.33

 
   

+

9

60.00

 
   

-

1

6.67

 
 

III

15

    
   

++

3

20.00

 
   

+

10

66.67

 
   

-

2

13.33

 
 

Control

15

    
   

++

0

0.00

 
   

+

6

40.00

 
   

-

9

60.00

 

PCNA

I

15

    
   

++

11

73.33

< 0.01

   

+

4

26.67

 
   

-

0

0.00

 
 

II

15

    
   

++

4

26.67

 
   

+

10

66.67

 
   

-

1

6.67

 
 

III

15

    
   

++

2

13.33

 
   

+

12

80.00

 
   

-

1

6.67

 
 

Control

15

    
   

++

0

0.00

 
   

+

5

33.33

 
   

-

10

66.67

 
  1. MMP-9: matrix metalloproteinase 9; VEGF: vascular endothelial growth factor; PCNA: proliferating cell nuclear antigen. Any slides that exhibited diffuse immunostaining or > 50% tumor cells were classified as (++), > 10% but < 50% as (+), and < 10% as (-). (P < 0.01, by Kruskal-Wallis H test)
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Journal of Translational Medicine

ISSN: 1479-5876

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