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Figure 6 | Journal of Translational Medicine

Figure 6

From: First-line chemoimmunotherapy in metastatic breast carcinoma: combination of paclitaxel and IMP321 (LAG-3Ig) enhances immune responses and antitumor activity

Figure 6

Correlation between the number of monocytes before treatment and tumor regression (Panel A). The absolute numbers of monocytes per μl of blood at D1 are plotted as a function of the percentages of change in the mean sum of tumor diameters at D170 versus D1 (correlation coefficient ρ = -0.4; p < 0.05). Correlation between the monocyte gain of function at D170 and tumor regression (Panel B). The monocyte gain of function calculated as the mean of the percentage increases of each of the eight activation markers in Figure 3A is plotted as a function of the percentages of change in the mean sum of tumor diameters at D170 versus D1 (correlation coefficient ρ = -0.44; p = 0.05).

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