Figure 2

Thermal effects of HIFU treatment. (A) Temperature profiles at the beam focus in MC-38 and B16 tumors when the transducer was run in continuous wave (CW) mode at a pressure level of P⁺ = 19.5/P^- = -7.2 MPa. Representative data of three independent experiments with consistent results are shown. (B) Lateral distribution of peak temperature in tumors produced by HIFU during 4-s exposures. Results are expressed as means ± SD out of four independent experiments. (C) Transversal and (D) longitudinal views of thermal lesions produced by HIFU with different treatment duration (4, 3, and 2 s) at above pressure level. The representative section from four treated mice with similar results is shown.