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Table 3 Summary statistics for performance of different normalization methods based on intra-class correlations (ICC s) computed for replicate miR microarray data obtained using 9 different renal cancer cell lines

From: Evaluation of normalization methods for two-channel microRNA microarrays

Methods

Min

Max

Median

Mean

SD

No.Norm

0.66

0.95

0.91

0.89

0.09

Mean

0.90

0.96

0.94

0.93

0.02

t.Mean

0.90

0.96

0.94

0.93

0.02

Median

0.90

0.96

0.94

0.93

0.02

Lowess

0.87

0.95

0.91

0.91

0.03

Quantile

0.88

0.94

0.92

0.91

0.02

Mean.10

0.90

0.95

0.93

0.93

0.02

Mean.20

0.90

0.96

0.93

0.93

0.02

Mean.30

0.90

0.96

0.94

0.93

0.02

t.Mean.10

0.90

0.95

0.93

0.93

0.02

t.Mean.20

0.90

0.96

0.93

0.93

0.02

t.Mean.30

0.90

0.96

0.94

0.93

0.02

Median.10

0.90

0.95

0.93

0.93

0.02

Median.20

0.90

0.95

0.93

0.93

0.02

Median.30

0.90

0.95

0.94

0.93

0.02

Lowess.10

0.75

0.92

0.89

0.86

0.06

Lowess.20

0.86

0.94

0.90

0.90

0.03

Lowess.30

0.87

0.95

0.90

0.91

0.03

Quantile.10

0.89

0.94

0.92

0.92

0.02

Quantile.20

0.89

0.95

0.93

0.92

0.02

Quantile.30

0.90

0.95

0.93

0.92

0.02

Quantile.40

0.89

0.95

0.93

0.92

0.02