Polymorphism | HCM* N=205 | Hypertensive LVH N = 145 | Controls N = 300 |
---|---|---|---|
5-HT2A (c.102 T/C) Rs6313 | |||
TT | 45 (22%) | 24 (17%) | 60 (20%) |
TC | 105 (51%) | 79 (54%) | 149 (50% |
CC | 55 (27%) | 42 (29%) | 91 (30%) |
T | 0.47 | 0.43 | 0.45 |
C | 0.53 | 0.57 | 0.55 |
5-HTT (l/s) Rs4795541 | |||
ll | 72 (35%) | 48 (33%) | 91 (30%) |
ls | 102 (50%) | 71 (49%) | 147 (49%) |
ss | 31 (15%) | 26 (18%) | 62 (21%) |
l | 0.60 | 0.58 | 0.55 |
s | 0.40 | 0.42 | 0.45 |
ACE (I/D) Rs4646994 | |||
DD | 72 (35%) | 54 (37%) | 119 (40%) |
ID | 100 (48%) | 68 (45%) | 135 (45%) |
II | 35 (17%) | 23 (15%) | 46 (15%) |
D | 0.59 | 0.61 | 0.62 |
I | 0.41 | 0.39 | 0.38 |
AGT (c.803 T/C) Rs699 | |||
MM | 64 (31%) | 54 (37%) | 95 (32%) |
MT | 100 (49%) | 68 (48%) | 145 (48%) |
TT | 41 (19%) | 22 (15%) | 60 (20%) |
M | 0.55 | 0.61 | 0.56 |
T | 0.45 | 0.39 | 0.44 |
AT1R (c.1166 A/C)# | |||
Rs5182 | |||
AA | 84 (41%) | 72 (50%) | 156 (53%) |
AC | 94 (46%) | 60 (41%) | 114 (37%) |
CC | 27 (13%) | 13 (9%) | 30 (10%) |
A | 0.64 | 0.70 | 0.71 |
C | 0.36 | 0.30 | 0.29 |