Skip to main content
Figure 5 | Journal of Translational Medicine

Figure 5

From: Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity

Figure 5

Differential regulation of elements that regulate gene transcription and translation in IRAK4-deficient monocytes. The relative expression (Y-axis) of (A) NFκB subunits NFκB1 (p105/50), NFκB2 (p100/52), RelA (p65), RelB & c-Rel, NFκB regulator IκBζ, and (B) translational suppressors IL-13RA & ZFP36L2 in IRAK4-deficient monocytes (black bars) and controls (white bars) was measured by real-time PCR following 4 hr incubation in the absence or presence of LPS (X-axis). Results show gene expression relative to unstimulated control monocytes and are representative of 3 independent experiments. Differences in expression were determined to be statistically significant by Student's two tailed T-test with a value of p < 0.15 (*), p < 0.1 (**), p < 0.05 (***) or p < 0.01 (****).

Back to article page