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Figure 1 | Journal of Translational Medicine

Figure 1

From: Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity

Figure 1

IRAK4-deficient mice maintain defence against Gram negative bacteria. IRAK4 -/- (dotted line) and age- and sex-matched C57BL wild type (solid line) mice were infected with S. typhimurium SL1344 and monitored for survival (y-axis) over time (x-axis). The result is representative of two independent experiments where lack of statistical significance (p = 0.69 and p = 0.13) for differential survival between two groups of eight infected mice was determined by the chi-square test.

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