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Table 2 Assays used to measure monkey genes on custom TaqMan low density array for monkey studies

From: Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood

Gene ID Use Species Assay ID (ABI)
18S Manufacturing QC Human Hs99999901_s1
CD19 Effects of IL21/Ab-01 Human Hs00174333_m1
CSF1 Effects of IL21/Ab-01 Human Hs00174164_m1
GUSb Normalizer Human Hs99999908_m1
GZMB Effects of IL21/Ab-01 Rhesus Rh02621701_m
ICOS Effects of IL21/Ab-01 Rhesus Rh02621771_m1
IFN γ Effects of IL21/Ab-01 Rhesus Rh02621721_m1
IL10 Effects of IL21/Ab-01 Human Hs00174086_m1
IL12B Effects of IL21/Ab-01 Human Hs00233688_m1
IL21R Effects of IL21/Ab-01 Human Hs00174086_m
IL2RA Effects of IL21/Ab-01 Human Hs00166229_m1
IL6 Effects of IL21/Ab-01 Rhesus Rh02621719_u1
IL7 Effects of IL21/Ab-01 Human Hs00174202_m1
IL8 Effects of IL21/Ab-01 Human Hs00174103_m1
PGK1 Normalizer Human Hs99999906_m1
PRF1 Effects of IL21/Ab-01 Human Hs00169473_m1
STAT3 Effects of IL21/Ab-01 Human Hs00234174_m1
TBX2 Effects of IL21/Ab-01 Human Hs00203436_m1
TNF Effects of IL21/Ab-01 Human Hs00174128_m1
ZNF592 Normalizer Human Hs00206029_m1
  1. In addition to the assays listed, assays for CCL19, CSF2, IL-17, and REN were run but found to be unreliable in these cynomolgus monkey samples and are not shown.