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Table 1 Assays used to measure human genes on custom TaqMan low density array for human studies

From: Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood

Gene

Gene Description

Assay ID (ABI)

18S*

Eukaryotic 18S rRNA

Hs99999901_s1

CCL3

chemokine (C-C motif ligand

Hs00234142_m1

CD19

CD19

Hs00174333_m

CXCL10

chemokine (C-X-C motif ligand 10)

Hs00171042_m1

CXCL11

chemokine (C-X-C motif ligand 11)

Hs00171138_m1

GNLY

Granulysin

Hs00246266_m1

GAPDH*

glyceraldehyde 3 phosphate dehydrogenase

Hs99999905_m1

GUSB*

glucuronidase, beta

Hs99999908_m1

GZMB

Granzyme B (cytotoxic T lymphocyte-associated serine esterase 1)

Hs00188051_m1

ICAM1

intercellular adhesion molecule 1 (CD54)

Hs00164932_m1

IFNg

interferon, gamma

Hs00174143_m1

IL10

interleukin 10

Hs00174086_m1

IL12A

interleukin 12A (natural killer cell stimulatory factor 1

Hs00168405_m1

IL1b

interleukin 1, beta

Hs00174097_m1

IL21R

interleukin 21 receptor

Hs00222310_m1

IL2RA

interleukin 2 receptor, alpha, CD25

Hs00166229_m1

IL6

interleukin 6

Hs00174131_m1

IL8

interleukin 8

Hs00174103_m1

PGK1*

phosphoglycerate kinase

Hs99999906_m1

PRF1

perforin 1 (pore forming protein)

Hs00169473_m1

STAT3

signal transducer and activator of transcription 3

Hs00234174_m1

TBX21

T box 21

Hs00203436_m1

TNF

tumor necrosis factor (TNF superfamily, member 2)

Hs00174128_m1

ZNF592*

zinc finger protein 592

Hs00206029_m1

  1. *Gene used as endogenous normalizer