Figure 4

Average percent inhibition of the expression level of 6 IL21-responsive genes. Percent inhibition values were calculated based on RQ (relative quantification) values of untreated control and rhIL21-treated samples for each of the 4 donors, and subsequently the mean and standard deviation were determined for each gene shown. A: Percent inhibition in presence of Ab-01. B: Percent inhibition in presence of control IgG₁TM. Data for the 0.1 μg/mL , 0.3 μg/mL and 1 μg/mL concentrations were generated using 4 donors. Data for the higher and the lower concentrations were generated using 2 donors.