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Table 1 Frequencies of TLR9 genotypes and haplotypes and risk of HIV-1 infection.

From: Toll-like receptor 9 polymorphisms influence mother-to-child transmission of human immunodeficiency virus type 1

SNP Genotypes Uninfected children
(n = 182) 		Infected children
(n = 118) 		OR 95% CI p
      LCL UCL  
c.4-44G > A(rs352139) GG 0.29 0.36 1    0.48
  GA 0.50 0.44 0.72 0.42 1.22  
  AA 0.31 0.20 0.80 0.42 1.53  
c.1635A > G(rs352140) AA 0.31 0.39 1    0.20
  AG 0.48 0.38 0.62 0.37 1.06  
  GG 0.21 0.23 0.86 0.46 1.62  
Haplotypes G;A 0.53 0.51 1    
  A;G 0.44 0.36 0.92 0.65 1.30 0.63*
  A;A 0.02 0.07 3.16 1.24 8.03 0.016*
  G;G 0.01 0.06 5.54 1.76 17.50 0.0038*
  1. LCL, lower confidence limit; UCL, upper confidence limit.
  2. * The significance level after Bonferroni correction for multiple testing is 0.017 instead of 0.05.
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Journal of Translational Medicine

ISSN: 1479-5876

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