From: Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients
Patients | Sex | Muscle | Lysosomal activity* | Muscle pathohistological aspects |
---|---|---|---|---|
DM1-1 | M | VL | xxxx | atrophy |
DM1-2 | M | VL | xxx | atrophy |
DM1-3 | M | VL | xx | mild atrophy |
DM1-4 | M | VL | xxxx | atrophy |
DM1-5 | M | VL | x | few atrophic fibers |
DM1-6 | F | VL | xxxx | severe atrophy |
DM1-7 | M | VL | absent | few atrophic fibers |