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Table 1 Pathohistological features of each DM1 specimens

From: Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients

Patients

Sex

Muscle

Lysosomal activity*

Muscle pathohistological aspects

DM1-1

M

VL

xxxx

atrophy

DM1-2

M

VL

xxx

atrophy

DM1-3

M

VL

xx

mild atrophy

DM1-4

M

VL

xxxx

atrophy

DM1-5

M

VL

x

few atrophic fibers

DM1-6

F

VL

xxxx

severe atrophy

DM1-7

M

VL

absent

few atrophic fibers

  1. Are shown the main pathohistological features of each DM1 specimens used in this study (sex, muscle, lysosomal activity and muscle pathohistological aspects). Muscle biopsies from VL of 1 female and 3 males have been used as control samples. (VL = Vastus Lateralis; M = Male; F = Female; * = Phosphatase activity present in atrophic fiber where autophagy is active.)