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Table 4 Genes down-regulated during DC maturation that could be used as biomarkers for assessing mDCs

From: Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies

  Fold decrease in gene expression for each maturation time*
Gene 4 hours 8 hours 24 hours
Genes down-regulated to a similar degree throughout maturation
CD1C 64.0 82.2 57.8
MYC 9.17 8.83 9.35
MAF 15.0 8.30 20.5
PTGS1 5.43 20.4 13.0
DOK2 8.78 7.03 9.63
Genes down-regulated most late in DC maturation
TGFBI 2.44 6.76 11.2
GATM 2.70 12.0 17.7
ARHGDIB 2.37 10.1 15.4
MRC1 NS 7.15 30.22
CLEC10A 3.82 28.2 43.5
  1. Fold-increase compared to iDCs.