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Table 1 Condensed data on patients histories and sample type

From: "Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression"

Gender Age Underlying
disease
Year of
Tx.
Kidney explant
or
biopsy
Why
indicated ?
Histo-
pathological
diagnosis
Tissue
samples
analyzed
n =
Symbol#in Figure8
female 60 Systemic Lupus erythematosus 1999* Kidney
explant
(01/2007)
Acute
renal failure
(Interstitial fibrosis, tubular atrophy)
Banff 2007,
5. II [34]
2 Black circle
Black
square
female 41 Systemic vasculitis (Purpura Schoenlein-Henoch) 1996 Kidney
explant
(01/2007)
Acute
renal failure
(Interstitial fibrosis, tubular atrophy)
Banff 2007,
5. II [34]
1 Black
triangle
male 17 Obstructive
uropathy
2006* Kidney
explant
(08/2007)
Impaired
kidney
function
(Interstitial fibrosis, tubular atrophy)
Banff 2007,
5. III [34]
2 Black
reverse
triangle
Black
rhomb
female 45 Chronic glomerulo-nephritis 1996 Indication
biopsy
(04/2007)
Impaired
kidney
function
Chronic tubulo-interstitial injury,
evidence for calcineurin
inhibitor
toxicity (CNIT)
1 White
circle
male 72 Chronic interstitial nephritis 2007 Indication
biopsy
(06/2007)
Impaired
kidney
function
Interstitial fibrosis, tubular atrophy, vasculopathy)
Banff 2007,
5. II [34] **
1 White
square
female 42 Systemic Lupus erythematosus 2005 Kidney
explant
(2005)
Allograft-steal-syndrome Diffuse tubular
damage
2 Black
circles
in plot "Control"
Not known
(anonymized)
RCC n.a. Tumor
nephrectomy
RCC Normal 1  
   RCC    RCC   1  
   RCC    RCC   1  
  1. 2nd allograft in patients history, ** = "old-for-old" kidney allocation, Tx. = transplantation, RCC = renal cell carcinoma, n.a. = not attributable. #Two symbols per case mean that 2 different tissue blocks were analyzed in the same patient.