Figure 2From: "Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression"Re-evaluation of miRNA-449a and miRNA-449b in fibroblasts. Three independent experiments confirmed significant down-regulation under hypoxia. All calculations were performed relative to RNU48 in the cell line F-18. ** = p < 0.01.Back to article page