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Table 2 Univariate and multivariate analysis of Cox proportional hazards model in NPC.

From: Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma

Characristics Hazard ratio 95% CI P-value
Univariate analysis    
   Gender (male vs. female) 0.422 0.232-0.770 0.005*
   Age (< 46 vs. ≥ 46) 1.721 1.085-2.729 0.021*
   WHO type (I vs. IV) 1.025 0.618-1.700 0.925
   Clinical stage (I + II vs. III + IV) 1.824 1.012-3.286 0.045*
   T stage (T1~2 vs. T3~4) 1.571 0.972-2.540 0.065
   N stage (N0 vs. N1~3) 0.936 0.568-1.544 0.796
   Recurrence (no vs. yes) 1.442 0.895-2.322 0.132
   Metastasis (no vs. yes) 2.466 1.412-4.304 0.002*
   LMP1 expression (low vs. high) 1.863 1.091-3.183 0.023*
   p-mTOR expression (low vs. high) 1.274 0.796-2.040 0.314
   p-P70S6K expression (low vs. high) 1.447 0.907-2.309 0.121
   p-4EBP1 expression (low vs. high) 1.920 1.154-3.195 0.012*
Multivariate analysis    
   Gender (male vs. female) 0.447 0.234-0.851 0.014*
   Metastasis (no vs. yes) 2.591 1.383-4.856 0.003*
   LMP1 expression (low vs. high) 2.056 1.161-3.641 0.013*
  1. * Statistically significant difference.