Microrna profiling analysis of differences between the melanoma of young adults and older adults

Table 9 Mirs Differentially Expressed Between Node Positive And Node Negative Adult (Mel 60) And Young Adult-Pediatric (Mel 30)

MiR	Parametric p-value	FDR	Permutation p-value	Geom mean of intensities in class 1	Geom mean of intensities in class 2	Geom mean of intensities in class 3	Geom mean of intensities in class 4
hsa-miR-204-4373094	0.00004	0.02784	< 1e-07	15.74986	11.70222	14.82001	6.94659
hsa-miR-30aSTAR-4373062	0.00035	0.11658	0.00010	7.67985	6.27768	7.25131	6.95430

The univariate F-test at the nominal significance level of 0.001 was performed among 4 classes: Class 1: Node-negative-Mel 30; Class 2: Node-negative-Mel 60; Class 3: Node-positive-Mel30; Class 4: Node-positive-Mel60. Permutation p-values for significant MiRs were computed based on 10000 random permutations. The Global test: probability of getting at least 2 genes significant by chance (at the 0.001 level) if there are no real differences between the classes was 0.137.

ISSN: 1479-5876