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Table 8 MiRs Significantly Differentially Expressed Between Stage I-II Adult Melanoma (Mel 60) And Stage I-II Young Adult-Pediatric Melanoma (Mel 30)

From: Microrna profiling analysis of differences between the melanoma of young adults and older adults

MiR Parametric p-value FDR Permutation p-value Geom mean of intensities in class 1 Geom mean of intensities in class 2 Fold-change
hsa-miR-30aSTAR-4373062 0.0001 0.0733 0.0022 7.7570 6.1934 1.2525
hsa-miR-30eSTAR-4373057 0.0003 0.1046 0.0022 6.8663 5.7540 1.1933
hsa-miR-10bSTAR-4395426 0.0007 0.1507 0.0022 10.5589 9.4540 1.1169
hsa-miR-337-5p-4395267 0.0009 0.1524 0.0022 17.2304 14.8781 1.1581
  1. Stage I-II Adult melanoma were compared with stage I-II pediatric melanoma by Two-sample T-test on the global data set of 666 miRs CT values normalized to MammU6 endogenous control (see analysis II). Class 1: Mel 30 Stage I-II; Class 2: Mel 60 Stage I-II. Exact permutation p-values for significant genes were computed based on 462 available permutations. Nominal significance level of each univariate test: 0.001. Global test: probability of getting at least 4 genes significant by chance (at the 0.001 level) if there are no real differences between the classes: 0.02597.