Microrna profiling analysis of differences between the melanoma of young adults and older adults

Table 6 Mirs Significantly Differentially Expressed Between Adult Nevus (Nevus 60) And Young Adult/Pediatric Nevus (Nevus 30)

Array A Hsa-miR Name-Assay#	FC (NEVUS60/NEVUS30)	Log2(FC)	p value	FDR (BH)	FC Bin
None significant	N/A	N/A		N/A
Array B Hsa-miR Name-Assay#	FC (NEVUS60/NEVUS30)	Log2(FC)	p value	FDR (BH)	FC Bin
hsa-miR-566-4380943	5.3288	2.4138	0.0359	0.9974	FC > 4
hsa-miR-374aSTAR-4395236	7.9972	2.9995	0.0371	0.9974	FC > 4

Array A: TLDA panel A (377 functionally defined microRNAs) array B: TLDA panel B (290 MicroRNAs whose function is not yet completely defined) TLDA A and B totaled 667 microRNA assays. FC: fold change; Pvalue student T test ≤ 0.05; FDR: false discovery rate; FC bin: Range of fold change. MirRs in bold font were found to be significantly differentially expressed between the two groups by the relative quantification (ABqPCR software-Analysis I) based method and by Class Comparison (BRB tools-Analysis II) based on absolute CT values normalized to endogenous control MammU6 (see materials and methods). N/A: not applicable.

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