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Table 3 Mirs Significantly Differentially Expressed Between Older Adult Melanoma (Mel 60) And Pediatric And Young Adult Melanoma (Mel 30)

From: Microrna profiling analysis of differences between the melanoma of young adults and older adults

Array A Hsa-miR Name-Assay# FC (MEL60/MEL30) Log2(FC) p value FDR (BH) FC Bin
hsa-miR-204-4373094 34.6805 5.1161 0.0007 0.1571 FC > 4
hsa-miR-199a-5p-4373272 4.3354 2.1162 0.0024 0.2701 FC > 4
hsa-miR-211-4373088 0.2785 -1.8441 0.0044 0.2701 FC 2.0-4.0
hsa-miR-574-3p-4395460 1.8143 0.8594 0.0053 0.2701 FC 1.6-2.0
hsa-miR-449a-4373207 0.3750 -1.4150 0.0057 0.2701 FC 2.0-4.0
hsa-miR-455-5p-4378098 0.4594 -1.1221 0.0070 0.2788 FC 2.0-4.0
hsa-miR-337-5p-4395267 2.6855 1.4252 0.0167 0.4867 FC 2.0-4.0
hsa-let-7b-4395446 1.9118 0.9349 0.0212 0.4867 FC 1.6-2.0
hsa-miR-140-3p-4395345 1.6343 0.7087 0.0221 0.4867 FC 1.6-2.0
hsa-miR-330-3p-4373047 1.9706 0.9786 0.0229 0.4867 FC 1.6-2.0
hsa-miR-489-4395469 1.8103 0.8563 0.0251 0.4867 FC 1.6-2.0
hsa-miR-24-4373072 0.6601 -0.5992 0.0264 0.4867 FC 1.2-1.6
hsa-miR-146b-3p-4395472 2.6336 1.3970 0.0283 0.4867 FC 2.0-4.0
hsa-miR-125b-4373148 1.8045 0.8516 0.0292 0.4867 FC 1.6-2.0
hsa-miR-192-4373108 0.6908 -0.5336 0.0334 0.4867 FC 1.2-1.6
hsa-miR-10b-4395329 2.2070 1.1421 0.0341 0.4867 FC 2.0-4.0
hsa-miR-199b-5p-4373100 2.3762 1.2486 0.0348 0.4867 FC 2.0-4.0
hsa-miR-19b-4373098 0.5745 -0.7996 0.0369 0.4873 FC 1.6-2.0
hsa-miR-423-5p-4395451 2.0952 1.0671 0.0398 0.4909 FC 2.0-4.0
hsa-miR-20a-4373286 0.5834 -0.7775 0.0421 0.4909 FC 1.6-2.0
hsa-miR-9-4373285 3.4546 1.7885 0.0433 0.4909 FC 2.0-4.0
Array B Hsa-miR Name-Assay# FC (MEL60/MEL30) Log2(FC) p value FDR (BH) FC Bin
hsa-miR-30aSTAR-4373062 2.2183 1.1494 0.0000 0.0021 FC 2.0-4.0
hsa-miR-10bSTAR-4395426 1.7444 0.8027 0.0022 0.0739 FC 1.6-2.0
hsa-miR-30eSTAR-4373057 1.6826 0.7507 0.0026 0.0739 FC 1.6-2.0
hsa-miR-409-3p-4395443 2.1484 1.1032 0.0049 0.1038 FC 2.0-4.0
hsa-miR-29cSTAR-4381131 2.2418 1.1647 0.0069 0.1151 FC 2.0-4.0
hsa-miR-125b-1STAR-4395489 2.7217 1.4445 0.0096 0.1341 FC 2.0-4.0
hsa-miR-432-4373280 2.6512 1.4066 0.0157 0.1808 FC 2.0-4.0
hsa-miR-505STAR-4395198 2.2251 1.1539 0.0193 0.1808 FC 2.0-4.0
hsa-miR-944-4395300 0.4042 -1.3068 0.0204 0.1808 FC 2.0-4.0
hsa-miR-766-4395177 2.6347 1.3976 0.0215 0.1808 FC 2.0-4.0
hsa-miR-214STAR-4395404 1.7814 0.8330 0.0252 0.1926 FC 1.6-2.0
hsa-miR-99bSTAR-4395307 1.4101 0.4958 0.0285 0.1993 FC 1.2-1.6
hsa-miR-572-4381017 0.4892 -1.0314 0.0411 0.2653 FC 2.0-4.0
hsa-miR-768-3p-4395188 1.2722 0.3474 0.0483 0.2896 FC 1.2-1.6
  1. Array A: TLDA panel A (377 functionally defined microRNAs) array B: TLDA panel B (290 MicroRNAs whose function is not yet completely defined) TLDA A and B totaled 667 microRNA assays. FC: fold change; Pvalue student T test ≤ 0.05; FDR: false discovery rate; FC bin: Range of fold change. MirRs in bold font were found to be significantly differentially expressed between the two groups by the relative quantification (ABqPCR software-Analysis I) based method and by Class Comparison (BRB tools-Analysis II) based on absolute CT values normalized to endogenous control MammU6 (see materials and methods). N/A: not applicable.