Treatmenta
|
nb
|
Mean vascular density/1000 μmc
|
95% Confidence interval
|
p versus PBS
|
---|
PBS
|
12
|
4.1
|
[3.3-5.0]
|
-
|
ALDHloLin-
|
5
|
5.4
|
[4.4-6.5]
|
0.279 (0.031)d
|
ALDHhiLin-
|
9
|
6.0
|
[5.0-7.0]
|
0.011 (0.001)d
|
- a NOD/SCID β2m null mice with AMI were transplanted with ALDHloLin- or ALDHhiLin- sorted human UCB cells or PBS. Frozen sections were stained with a mouse specific CD31 antibody and visualized with DAB+ chromagen.
- b Number of hearts analyzed pr. group; 10 randomly selected visual fields (40× magnification) in the tissue sub-served by the infarct related artery were analyzed from each heart.
- c CD31 positive vascular structures with a well defined tubular morphology or an open lumen or structures with a linear extension equal to or larger than 50 μm were included.
- d p-value after correction for outliers.