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Table 2 Correlation of ZAP-70 analyses with IGHV mutational status as prognostic markers.

From: Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells

 

ISO-method

T-method

T/B Ratio-method

<11

≥ 11

% conc

<20

≥ 20

% conc

≥ 3

<3

% conc

M IGHV

90

25

75

92

23

74

79

36

67

UM IGHV

17

41

(p < 0.00001)

21

37

(p < 0.00001)

21

37

(p < 0.00001)

  1. Abbreviations: M IGHV, mutated IGHV genes status; UM IGHV, unmutated IGHV genes status; % conc, overall percentage of concordancy between the two prognostic parameters.
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Journal of Translational Medicine

ISSN: 1479-5876

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