Table 3 Adjusted Hazard Ratios (95% Confidence Intervals) from Cox Regression
From: Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival
| Â | Death from Breast Cancer | P-value | Death from Any Cause | P-value |
|---|---|---|---|---|
Fractal dimension | Â | Â | Â | Â |
   < 1.56 | 1.0 |  | 1.0 |  |
   1.56 - 1.75 | 1.9 (1.1, 3.5) | 0.043 | 2.0 (1.2, 3.5) | 0.011 |
   >1.75 | 2.6 (1.4, 4.8) | 0.002 | 2.7 (1.6, 4.7) | < 0.001 |
Age | Â | Â | Â | Â |
   ≤ 55 years | 1.0 |  | 1.0 |  |
   >55 years | 1.8 (0.8, 4.2) | 0.14 | 2.7 (1.2, 5.9) | 0.01 |
Size of tumour | Â | Â | Â | Â |
   ≤ 2 cm | 1.0 |  | 1.0 |  |
   >2 cm | 1.0 (0.6, 1.6) | 0.96 | 1.0 (0.7, 1.6) | 0.88 |
Grade of tumour | Â | Â | Â | Â |
   1 & 2 | 1.0 |  | 1.0 |  |
   3 | 2.1 (1.1, 3.7) | 0.01 | 1.7 (1.1, 3.0) | 0.047 |
Lymph node status | Â | Â | Â | Â |
   Negative | 1.0 |  | 1.0 |  |
   Positive | 3.1 (1.9, 5.1) | < 0.001 | 2.6 (1.7, 4.1) | < 0.001 |
Estrogen-receptor status | Â | Â | Â | Â |
   Positive | 1.0 |  | 1.0 |  |
   Negative | 1.6 (0.7, 3.7) | 0.27 | 1.5 (0.7, 3.2) | 0.26 |
HER-2/neu status | Â | Â | Â | Â |
   Positive | 1.0 |  | 1.0 |  |
   Negative | 1.1 (0.5, 2.5) | 0.87 | 1.1 (0.5, 2.4) | 0.70 |