Skip to main content
Figure 2 | Journal of Translational Medicine

Figure 2

From: Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors

Figure 2

Rapamycin treated Tsc2+/- mice show a higher percentage of cystic and pre-papillary cystadenomas and a smaller percentage of papillary and solid cystadenomas. The absolute score per kidney for each cystadenoma subtype is shown in Figure 2a, and the percent of total score per kidney for each cystadenoma subtype is shown in Figure 2b. For a description of each subtype, see Additional File 2. Papillary cystadenomas contribute the largest percentage to total score per kidney in untreated A/J and C57BL/6 cohorts at all time points. Pre-papillary cystadenomas contribute the largest percentage to total score per kidney in A/J cohorts treated with rapamycin. Treatment with rapamycin results in a decrease in the percentages of papillary and solid cystadenomas and an increase in the percentages of pre-papillary and cystic cystadenomas.

Back to article page