Table 3 Multivariate analyses of factors associated with OS and LMFS

Gender (female vs. male)

1.954 (0.841-4.538)

0.119

0.333 (0.083-1.335)

0.121

Age (< 60 y vs. ≥ 60 y)

0.504 (0.227-1.116)

0.091

0.881 (0.267-2.906)

0.835

Invasive depth (T4 vs. T3)

1.941 (0.693-5.436)

0.207

0.846 (0.171-4.190)

0.838

Site of primary tumors (right vs. left)

2.184 (0.981-4.859)

0.056

1.009 (0.298-3.414)

0.989

Grade (G3 vs. G2 vs. G1)

1.224 (0.457-3.281)

0.688

1.616 (0.345-7.575)

0.543

Pathologic Classification (mucoid + signet ring vs. papillary + tubular)

2.364 (0.787-7.100)

0.125

0.537 (0.071-4.061)

0.547

Growth patterns (infiltrating vs. pushing)

0.700 (0.295-1.662)

0.419

2.650 (0.551-12.746)

0.224

CD68TF_Hotspot group (high vs. low)

0.433 (0.194-0.966)

0.041*

0.265 (0.078-0.900)

0.033*

Liver metastasis (yes vs. no)

8.144 (3.276-20.250)

0.000**

NA

NA