Table 2 Univariate analyses of factors associated with OS and LMFS.

Gender (female vs. male)

1.157 (0.562-2.381)

0.693

0.416 (0.114-1.510)

0.182

Age (< 60 y vs. ≥ 60 y)

0.732 (0.352-1.519)

0.402

0.704 (0.230-2.153)

0.538

Invasive depth (T4 vs. T3)

1.023 (0.392-2.674)

0.962

0.902 (0.200-4.068)

0.893

Sites of primary tumors (right vs. left)

2.271 (1.093-4.717)

0.028*

0.815 (0.267-2.491)

0.720

Grade (G3 vs. G2 vs. G1)

1.519 (0.715-3.224)

0.277

1.036 (0.324-3.311)

0.953

Pathologic classification (mucoid + signet ring vs. papillary + tubular)

2.415 (1.129-5.168)

0.023*

1.148 (0.316-4.171)

0.834

Growth pattern (infiltrating vs. pushing)

0.817 (0.389-1.718)

0.595

2.709 (0.600-12.223)

0.195

CD68TF_Hotspot (4 vs. 3 vs. 2 vs.1)

0.568 (0.393-0.822)

0.003*

0.594 (0.344-1.025)

0.061

CD68TF_Hotspot group (high vs. low)

0.288 (0.139-0.600)

0.001*

0.324 (0.106-0.991)

0.048*

Hepatic metastasis (yes vs. no)

5.852 (2.737-12.511)

0.000**

NA

NA