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Table 2 Univariate analyses of factors associated with OS and LMFS.

From: The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer

Variable OS (n = 98) LMFS (n = 98)
  HR, (95% CI) P value HR, (95% CI) P value
Gender (female vs. male) 1.157 (0.562-2.381) 0.693 0.416 (0.114-1.510) 0.182
Age (< 60 y vs. ≥ 60 y) 0.732 (0.352-1.519) 0.402 0.704 (0.230-2.153) 0.538
Invasive depth (T4 vs. T3) 1.023 (0.392-2.674) 0.962 0.902 (0.200-4.068) 0.893
Sites of primary tumors (right vs. left) 2.271 (1.093-4.717) 0.028* 0.815 (0.267-2.491) 0.720
Grade (G3 vs. G2 vs. G1) 1.519 (0.715-3.224) 0.277 1.036 (0.324-3.311) 0.953
Pathologic classification (mucoid + signet ring vs. papillary + tubular) 2.415 (1.129-5.168) 0.023* 1.148 (0.316-4.171) 0.834
Growth pattern (infiltrating vs. pushing) 0.817 (0.389-1.718) 0.595 2.709 (0.600-12.223) 0.195
CD68TFHotspot (4 vs. 3 vs. 2 vs.1) 0.568 (0.393-0.822) 0.003* 0.594 (0.344-1.025) 0.061
CD68TFHotspot group (high vs. low) 0.288 (0.139-0.600) 0.001* 0.324 (0.106-0.991) 0.048*
Hepatic metastasis (yes vs. no) 5.852 (2.737-12.511) 0.000** NA NA
  1. Univariate analysis, Cox proportional hazards regression model. Abbreviations: HR, hazard ratio; CI, confidence interval; NA, not assessment. *: p < 0.05; **: p < 0.001.