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Table 2 TG-induced expansion (fold-increase) of PBMC from healthy donors.

From: Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures

Culture
condition
T = 7d T = 14d T = 21d
lowαCD3
(50 ng/ml)
1.70
(1.2-2.3)
8.47
(3.9-15.58)
22.21
(9.78-33.04)
lowTG
(50 ng/ml)
2.90
(1.72-2.94)
8.74
(7.85-16.61)
30.56
(18.91-33.65)
intαCD3
(250 ng/ml)
0.30
(0.24-1.35)
2.63
(0.26-5.01)
14.3
(10.05-15.41)
intTG
(250 ng/ml)
2.50
(2.47-3.56)
14.86*,^
(7.21-17.45)
33.47§,^
(23.72-40.77)
hiαCD3
(500 ng/ml)
0.59
(0.28-0.9)
5.28
(5.03-8.30)
11.75
(9.80-12.05)
hiTG
(500 ng/ml)
2.63
(2.05-3.02)
11.96**,^
(6.01-17.91)
46.08§§,^^
(34.84-57.31)
  1. Fold expansion of PBMC cells in culture has been calculated by dividing the absolute number of cells at days 7, 14 and 21 by the absolute number of cells at day 0. * and §p < 0.05 compared with intαCD3 mAb; ** and §§ p < 0.01 compared with hiαCD3 mAb. ^ p < 0.05 compared with lowαCD3 mAb; ^^ p < 0.01 compared with lowαCD3 mAb.