Figure 5
Expression of NK-cell inhibitory/activating receptors on CIK cells generated with TG. After 21 days of culture in the presence of either TG or αCD3 mAb, cells were harvested and labeled with mAb recognizing NK inhibitory receptors (NKG2A/CD94), NK activating receptors (NKG2D), KIR (CD158a, CD158b) and NK triggering receptors (NKp46). A representative experiment out of 10 with similar results is shown. Quadrant markers were set according to the proper isotypic control (not shown). The percentage of cells staining positively for a given antigen is indicated.