From: Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque
Agonist
P-selectin expression (% positive cells)
Control
Stimulated
TRAP (5 μM)
1.6 ± 0.6
6.8 ± 3.4
TRAP+NSC23766 (300 μM)
1.4 ± 0.6
Collagen (5 μg/ml)
1.7 ± 0.9
8 ± 2.6
Collagen+NSC23766 (300 μM)
2.9 ± 2