Figure 1
Effect of NSC23766 on stimulus-induced platelet aggregation in blood. (A) Hirudin-anticoagulated blood was pretreated with NSC23766 (300 μM) or solvent (H2O) for 5 min whilst stirring at 37°C before stimulation with TRAP (5 μM), collagen (0.5 μg/ml) or atherosclerotic plaque homogenate (0.62 mg/ml) for 5 min; representative impedance tracings. (B) Dose-response curves of NSC23766; values are mean ± SD (n = 4).