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Table 4 Zinc Transporters (Importers) and Cancer

From: Zinc in innate and adaptive tumor immunity

Cancer Transporter Comment References
Erythroleukemia ZIP1 In the vesicular compartment and partly in the ER in adherent cells [99]
Squamous cell carcinoma ZIP2 mRNA is induced by contact inhibition and serum starvation [202]
Prostate ZIP1, ZIP2, ZIP3 Down-regulated in malignant cells [203]
Pancreas ZIP4 Over-expression is linked to increased cell proliferation [106]
Breast ZIP6, ZIP10 Expression is linked to metastasis to lymph node [204, 205]
Tamoxifen resistant breast cancer ZIP7 Increased levels results in increased growth and invasion [182, 206, 207]