Cohort | Toxicity G3-G4 | Â | Toxicity G1-G2 | ||||||
---|---|---|---|---|---|---|---|---|---|
 | Neutropenia | Thrombopenia | Anemia | Others |  | Neutropenia | Thrombopenia | Anemia | Others |
Cohort A Schedule 1,8,28 | 1/7 pts | 3/7 pts | 0/7 pts | 0/7 | Â | 4/7 | 4/7 | 4/7 | 4/7 (1 transaminase increasing; 3 nausea-vomiting) |
Cohort B Schedule 1, 21 | 0/7 pts | 1/7 pts | 0/7 pts | 0/7 | Â | 6/7 | 5/7 | 5/7 | 5/7 (1 asthenia; 4 nausea-vomiting) |