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Figure 5 | Journal of Translational Medicine

Figure 5

From: Effects of pegylated G-CSF on immune cell number and function in patients with gynecological malignancies

Figure 5

Phenotypic features of DC-like cells from patients receiving pegfilgrastim. Monocytes were purified from the peripheral blood of patients given pegfilgrastim and were cultured in the presence of either pre-G-CSF or post-G-CSF serum (20% v/v) for 6 days, as detailed in Materials and Methods. Control cultures consisted of immunogenic DC preparations that were differentiated with GM-CSF and IL-4 without the provision of additional maturation stimuli (GM4DC). Panel A: Percentage of cells staining positively for a given antigen in a representative experiment out of 12 with similar results. Panel B: Relative expression of informative differentiation antigens. Median values and interquartile range recorded in 12 independent experiments. *denotes a p value < 0.05 compared with the other time-points.

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