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Table 1 Demographic, clinical and laboratory parameters of CLL patients

From: Quantification of newly produced B and T lymphocytes in untreated chronic lymphocytic leukemia patients

Patients 1 2 3 4 5 6 7 8 9 10 11 12 Controls
(range)
Age 68 65 69 68 48 77 73 53 67 53 56 66 50-69
Gender M* M M M M M M F M M M F na
Rai stage 0 0 0 0 0 0 0 0 0 0 0 0 na
Binet stage A A A A A A A A A A A A na
Lymphocytes/μL 12 350 30 210 27 500 8 050 5 290 38 470 47 810 14 330 6 030 10 980 24 680 11 360 950-4 612
Haemoglobin (g/dL) 15.6 13.4 14.0 14.2 14.4 13.5 11.7 15.5 16.0 15.2 14.5 14.2 14-18
Platelets (103/μL) 236 216 173 128 247 211 139 160 150 147 220 183 130-400
β2-microglobulin (mg/L) 2.0 2.5 2.8 2.2 1.9 2.1 4.7 2.0 3.7 2.4 2.5 2.4 < 2.5
Direct Antiglobulin Test neg neg neg neg neg neg neg neg neg neg neg neg neg
IgVH mutational status mut unm mut unm mut unm mut unm mut unm mut mut na
FISH del13q14 neg del13q14 neg neg del13q14 del13q14 del13q14 neg neg neg del13q14 na
IgG (mg/dL) 979 1 104 936 857 740 908 672 551 702 904 860 1 448 690-1 500
Clonally expanded chains Igλ Igκ Igκ Igλ Igλ Igλ Igκ Igκ Igκ Igκ Igκ Igκ na
IgA (mg/dL) 190 368 107 186 113 86 234 40 123 211 243 106 85-410
IgM (mg/dL) 38 58 38 53 113 15 36 36 17 46 13 95 40-240
  1. *Abbreviations: M, male; F, female; na, not applicable; neg, negative; IgVH, immunoglobulin heavy chain variable genes; mut, mutated; unm, unmutated; FISH, fluorescence in situ hybridization.