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Table 1 Clinicopathologic features and CEA* mRNA expression detected by real-time RT-PCR

From: Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma

Characteristics

Total number

(N = 123)

CEA mRNA

P value

Positive

(n = 45)

Negative

(n = 78)

Age

    

   ≤40

13

3

10

 

   41-50

20

9

11

 

   51-60

39

9

30

 

   61-70

42

18

24

 

   >70

9

6

3

0.063

Sex

    

   Female

41

12

29

 

   Male

82

33

49

0.234

Tumor

    

   T1

10

6

4

 

   T2

16

3

13

 

   T3

73

26

47

 

   T4

24

10

14

0.001

Lymph node

    

   N0

31

11

20

 

   N1

43

15

28

 

   N2

29

8

21

 

   N3

20

11

9

0.261

Pathologic TNM# stage

    

   I

16

7

9

 

   II

21

6

15

 

   III

51

17

34

 

   IV

35

15

20

0.623

Histology subtype

    

   Well differentiated adenocarcinoma

3

1

2

 

   Moderately differentiated adenocarcinoma

27

7

20

 

   Poorly differentiated adenocarcinoma

93

37

56

0.418

Serum CEA condition

    

   Positive

30

11

19

 

   Negative

93

34

59

0.992

Recurrence

    

   Yes

44

25

19

 

   No

79

20

59

0.001

Modes of recurrence

    

Local recurrence

8

4

4

 

   Abdominal cavity

9

6

3

 

   Liver

8

5

3

 

   pelvic

6

3

3

 

   Multiple sites

10

5

5

 

   others

3

2

1

0.959

  1. * Carcinoembryonic antigen
  2. # TNM denotes tumor-node-metastasis
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Journal of Translational Medicine

ISSN: 1479-5876

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