|
Variables
|
OS
|
DFS
|
|---|
|
N
|
Median (Range)
|
P *
|
N
|
Median (Range)
|
P *
|
|---|
|
Clinico-pathological data
| | | | | | |
|
Pathological types
| | | | | | |
|
Adenocarcinoma
|
25
|
19.0 (1.5-52.5)
|
0.860
|
20
|
14.0 (1.0-52.5)
|
0.796
|
|
Nonadenocarcinoma
|
12
|
22.0 (3.0-53.0)
| |
9
|
25.0 (2.0-53.0)
| |
|
Serosa invasion
| | | | | | |
|
No (T1/T2)
|
8
|
44.0 (2.0-52.5)
|
0.024
|
7
|
45.0 (13.0-52.5)
|
0.038
|
|
Yes (T3/T4)
|
29
|
13.0 (1.5-53.0)
| |
22
|
9.3 (1.0-53.0)
| |
|
Lymph node metastasis
| | | | | | |
|
No
|
10
|
22.0 (1.5-53.0)
|
0.213
|
9
|
38.0 (6.0-52.5)
|
0.681
|
|
Yes
|
27
|
12.5 (2.0-33.0)
| |
20
|
11.3 (1.0-53.0)
| |
|
Distant metastasis
| | | | | | |
|
M0
|
29
|
22.0 (1.5-53.0)
|
0.021
| | | |
|
M1
|
8
|
12.5 (2.0-33.0)
| | | | |
|
TNM stage
| | | | | | |
|
Early
|
11
|
44.0 (11.0-52.5)
|
0.009
|
11
|
46.0 (42.0-52.5)
|
0.006
|
|
Advanced
|
26
|
12.0 (1.5-53.0)
| | |
18
|
26.5 (8.0-51.5)
|
|
Immunohistochemistry (IHC)
| | | | | | |
|
MMP9
| | | | | | |
|
Positive
|
30
|
13.5 (1.5-52.0)
|
0.036
|
23
|
9.5 (1.0-51.5)
|
0.171
|
|
Negative
|
7
|
44.0 (13.0-53.0)
| |
6
|
43.5 (25.0-53.0)
| |
|
MMP2
| | | | | | |
|
Positive
|
20
|
14.0 (1.5-53.0)
|
0.867
|
13
|
9.0 (1.0-53.0)
|
0.395
|
|
Negative
|
17
|
22.0 (7.0-51.5)
| |
16
|
20.0 (4.0-51.5)
| |
|
Type IV collagen
| | | | | | |
|
Positive
|
30
|
25.5 (1.5-53.0)
|
0.044
|
25
|
19.0 (1.0-53.0)
|
0.646
|
|
Negative
|
7
|
10.0 (2.0-42.0)
| |
4
|
9.3 (2.0-42.0)
| |
|
Macrophages
| | | | | | |
|
Low density
|
16
|
40.5 (1.5-53.0)
|
0.056
|
16
|
37.0 (1.0-53.0)
|
0.013
|
|
High density
|
21
|
13.0 (2.0-53.0)
| |
21
|
9.5 (2.0-49.0)
| |
|
MVD
| | | | | | |
|
Low
|
19
|
39.0 (11.0-53.0)
|
0.001
|
16
|
21 (3.0-53)
|
0.209
|
|
High
|
18
|
8.5 (1.5-53.0)
| |
13
|
6.0 (0.5-49.0)
| |
- * Log-rank test (Two-tailed), bold font representing significant data (P < 0.05).
