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Figure 4 | Journal of Translational Medicine

Figure 4

From: Inflammatory mechanisms in ischemic stroke: therapeutic approaches

Figure 4

Regulatory T (T reg ) cells protect the brain after stroke. Experiments by Liesz et al. [57] show that Treg cells prevent delayed lesion expansion in an IL-10-dependent manner in a mouse model of acute ischemic stroke. They also reduce the proinflammatory cytokine levels during the early postischemic inflammatory phase. Injection of IL-10 in the brain reduces infarct volume. Reprinted by permission from Macmillan Publishers Ltd: Nature Medicine 15, 138-139 Copyright 2009.

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