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Table 2 Distribution of metastatic tumor determined on histology and imaging

From: Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation

  Group 1 Group 2 Group 3
% Day 1 (n = 4) Day 3 (n = 4) Week 1 (n = 5) Week 2 (n = 3) Week 3 (n = 1) (n = 8) (n = 5)
Braina 0 0 80 100 100 87.5 80
Spinal Corda 0 0 80 100 100 87.5 80
Lunga 0 0 0 20 0 50 60
Livera 0 0 20 33.3 100 0 0
Kidneya 0 0 60 100 100 87.5 60
Lymph Nodea 0 0 100 100 100 100 100
Heart 0 0 0 0 0 0 0
Boneb 100 100 100 100 100 100 80
  1. Note. a. Tumor cells within the vasculature or tissue on day 1 and 3 were not counted.
  2. b. Positive tumor cells detected by immunohistochemical staining of bone marrow sample were considered as positive lesion on group 1 rats. Group 2 rats underwent histological examination of long bone and spine for bone tumor determination. In group 3 rats, bone tumor lesions were determined on MRI and BLI.