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Table 2 Distribution of metastatic tumor determined on histology and imaging

From: Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation

 

Group 1

Group 2

Group 3

%

Day 1 (n = 4)

Day 3 (n = 4)

Week 1 (n = 5)

Week 2 (n = 3)

Week 3 (n = 1)

(n = 8)

(n = 5)

Braina

0

0

80

100

100

87.5

80

Spinal Corda

0

0

80

100

100

87.5

80

Lunga

0

0

0

20

0

50

60

Livera

0

0

20

33.3

100

0

0

Kidneya

0

0

60

100

100

87.5

60

Lymph Nodea

0

0

100

100

100

100

100

Heart

0

0

0

0

0

0

0

Boneb

100

100

100

100

100

100

80

  1. Note. a. Tumor cells within the vasculature or tissue on day 1 and 3 were not counted.
  2. b. Positive tumor cells detected by immunohistochemical staining of bone marrow sample were considered as positive lesion on group 1 rats. Group 2 rats underwent histological examination of long bone and spine for bone tumor determination. In group 3 rats, bone tumor lesions were determined on MRI and BLI.