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Table 1 Experimental Design

From: Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation

Days Group A rats (n = 18) Group B rats (n = 8) Group C rats (n = 5)
Prior to infusion of cells MRI baseline MRI Baseline MRI Baseline
Day 0 IC injection 3 × 106 FEPro labeled 231BRL 106 FEPro labeled 231BRL 106 unlabeled 231BRL
Day 1 MRI and BLI Euthanized 4 of 18 rats MRI and BLI MRI and BLI
Day 2 -- MRI and BLI MRI and BLI
Day 3 MRI and BLI Euthanized 4 of 14 rats MRI and BLI MRI and BLI
Week 1 MRI and BLI Euthanized 5 of 10 rats MRI and BLI MRI and BLI
Week 2 MRI and BLI Euthanized 3 of 5 rats MRI and BLI MRI and BLI
Week 3 MRI and BLI Euthanized all rats MRI and BLI MRI and BLI
Week 4   - Euthanize 8 rats - - Euthanize 5 rats -