Table 1 Experimental Design
Days | Group A rats (n = 18) | Group B rats (n = 8) | Group C rats (n = 5) |
|---|---|---|---|
Prior to infusion of cells | MRI baseline | MRI Baseline | MRI Baseline |
Day 0 IC injection | 3 × 106 FEPro labeled 231BRL | 106 FEPro labeled 231BRL | 106 unlabeled 231BRL |
Day 1 | MRI and BLI Euthanized 4 of 18 rats | MRI and BLI | MRI and BLI |
Day 2 | -- | MRI and BLI | MRI and BLI |
Day 3 | MRI and BLI Euthanized 4 of 14 rats | MRI and BLI | MRI and BLI |
Week 1 | MRI and BLI Euthanized 5 of 10 rats | MRI and BLI | MRI and BLI |
Week 2 | MRI and BLI Euthanized 3 of 5 rats | MRI and BLI | MRI and BLI |
Week 3 | MRI and BLI Euthanized all rats | MRI and BLI | MRI and BLI |
Week 4 | Â | - Euthanize 8 rats - | - Euthanize 5 rats - |