Figure 3
Bioluminescence imaging and MRI obtained from representative a rat from Group 2 and Group 3. First column contains representative images from Group 3 rats that received unlabeled breast cancer cells. Columns 2-6 (left to right) contain serial scans from Group 2 rat that received 106 FEPro labeled 231BRL cells. At day 2, BLI demonstrate intense photon flux from the brain from both groups of animals. T2*-weighted images demonstrate the presence of numerous hypointense voxels containing labeled cells (middle row, arrowhead). Arrows on T2-weighted images indicates growing metastatic breast cancer that can be seen as early as 2 weeks after infusion of cells.