Figure 3
From: Main roads to melanoma
iNOS pathway. The functional correlation between the IRF1-activating events (mainly, through an induction regulated by NF-kB, TNF-α, and INF-γ mediators) and expression levels of iNOS is shown. CALM, calmodulin; IkB, inhibitor of kB protein; IKK, inhibitor-of-kB-protein kinase; IRF1, interferon regulatory factor-1; LPS, lipopolysaccharide; NO, nitric oxide; STAT1, signal transducer and activator of transcription 1.