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Table 1 The first 40 up-regulated genes in HCV-related HCC

From: Gene profiling, biomarkers and pathways characterizing HCV-related hepatocellular carcinoma

Gene Name Description
1 RYBP RING1 and YY1 binding protein (RYBP)
2 ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
3 TMC transmembrane channel-like 7 (TMC7)
4 ZNF567 zinc finger protein 567 (ZNF567
5 GPR108 G protein-coupled receptor 108 (GPR108), transcript variant 1
6 CD19 CD19 molecule
7 SPINK1 serine peptidase inhibitor, Kazal type 1
8 CDC2L6 cell division cycle 2-like 6 (CDK8-like)
9 RSRC1 arginine/serine-rich coiled-coil 1 (RSRC1)
10 METAP methionyl aminopeptidase 1
11 GPC3 glypican 3
12 SNHG11 Small nucleolar RNA host gene (non-protein coding) 11
13 RY1 putative nucleic acid binding protein RY-1 (RY1)
14 CRELD2 cysteine-rich with EGF-like domains 2 (CRELD2)
15 GLUL glutamate-ammonia ligase (glutamine synthetase)
16 SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1)
17 TRMT6 tRNA methyltransferase 6 homolog (S. cerevisiae)
18 UNC13D unc-13 homolog D (C. elegans) (UNC13D)
19 E4F1--E4F E4F transcription factor 1 (E4F1)
20 SLC22A2 solute carrier family 22 (organic cation transporter), member 2 (SLC22A2)
21 CNIH4 cornichon homolog 4 (Drosophila) (CNIH4)
22 TK1 thymidine kinase 1, soluble (TK1)
23 MAFB v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
24 PPP1CB protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), transcript variant 3
25 DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 (DNTTIP2)
26 ARID4B AT rich interactive domain 4B (RBP1-like) (ARID4B), transcript variant 1
27 SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c,
28 PRO1386 PRO1386 protein
29 TRIOBP TRIO and F-actin binding protein (TRIOBP), transcript variant 1
30 VARS valyl-tRNA synthetase
31 ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
32 TERF1 telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 2
33 PURA purine-rich element binding protein A (PURA)
34 TUBA1B tubulin, alpha 1b
35 SNRPE small nuclear ribonucleoprotein polypeptide E
36 RRAGD Ras-related GTP binding D
37 VWF von Willebrand factor
39 GLRX3 glutaredoxin 3 (GLRX3)
40 ILF2 interleukin enhancer binding factor 2, 45 kDa