Table 1 The first 40 up-regulated genes in HCV-related HCC
From: Gene profiling, biomarkers and pathways characterizing HCV-related hepatocellular carcinoma
N° | Gene Name | Description |
|---|---|---|
1 | RYBP | RING1 and YY1 binding protein (RYBP) |
2 | ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
3 | TMC | transmembrane channel-like 7 (TMC7) |
4 | ZNF567 | zinc finger protein 567 (ZNF567 |
5 | GPR108 | G protein-coupled receptor 108 (GPR108), transcript variant 1 |
6 | CD19 | CD19 molecule |
7 | SPINK1 | serine peptidase inhibitor, Kazal type 1 |
8 | CDC2L6 | cell division cycle 2-like 6 (CDK8-like) |
9 | RSRC1 | arginine/serine-rich coiled-coil 1 (RSRC1) |
10 | METAP | methionyl aminopeptidase 1 |
11 | GPC3 | glypican 3 |
12 | SNHG11 | Small nucleolar RNA host gene (non-protein coding) 11 |
13 | RY1 | putative nucleic acid binding protein RY-1 (RY1) |
14 | CRELD2 | cysteine-rich with EGF-like domains 2 (CRELD2) |
15 | GLUL | glutamate-ammonia ligase (glutamine synthetase) |
16 | SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1) |
17 | TRMT6 | tRNA methyltransferase 6 homolog (S. cerevisiae) |
18 | UNC13D | unc-13 homolog D (C. elegans) (UNC13D) |
19 | E4F1--E4F | E4F transcription factor 1 (E4F1) |
20 | SLC22A2 | solute carrier family 22 (organic cation transporter), member 2 (SLC22A2) |
21 | CNIH4 | cornichon homolog 4 (Drosophila) (CNIH4) |
22 | TK1 | thymidine kinase 1, soluble (TK1) |
23 | MAFB | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) |
24 | PPP1CB | protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), transcript variant 3 |
25 | DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 (DNTTIP2) |
26 | ARID4B | AT rich interactive domain 4B (RBP1-like) (ARID4B), transcript variant 1 |
27 | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, |
28 | PRO1386 | PRO1386 protein |
29 | TRIOBP | TRIO and F-actin binding protein (TRIOBP), transcript variant 1 |
30 | VARS | valyl-tRNA synthetase |
31 | ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
32 | TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant 2 |
33 | PURA | purine-rich element binding protein A (PURA) |
34 | TUBA1B | tubulin, alpha 1b |
35 | SNRPE | small nuclear ribonucleoprotein polypeptide E |
36 | RRAGD | Ras-related GTP binding D |
37 | VWF | von Willebrand factor |
39 | GLRX3 | glutaredoxin 3 (GLRX3) |
40 | ILF2 | interleukin enhancer binding factor 2, 45 kDa |