Skip to main content
Figure 5 | Journal of Translational Medicine

Figure 5

From: Regulatory activity of azabisphosphonate-capped dendrimers on human CD4+ T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy

Figure 5

Specific and competitive interaction of azabisphonate dendrimers with pure CD4+ T cells. a) Equilibrium binding curve (dots) and equation of the two-component binding interaction after software modelling (Values of the constants are detailed on the graph). b) Competition with 20 μM 3a-G1 increases Kd showing that both dendrimers are competing for same binding sites. c) Equilibrium binding curve of Julo-3a-G1, Kd and Bmax, comparing CD4, CD8 T cells and NK cells using monocyte depleted PBMCs.

Back to article page