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Table 1 TRIP-Br2 expression profiling in human tissues by interrogation of the Novartis GNF SymAtlas v1.2.4 microarray database

From: TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors

Human tissues TRIP-Br2 gene expression
Bronchial epithelial cells ++
Lung +
Whole brain +
Bone marrow* +++
Thymus* ++++
Lymph node ++
Tonsil* +++
Heart +
Liver +
Kidney +
Skin +
Pancreas +
Skeletal muscle +
Cardiac myocytes +
Smooth muscle* +++
Placenta* +++
Prostate ++
Uterus ++
Ovary +
Testis +
Lymphohematopoietic cell lineages  
BM-CD34+ cells* ++++
BM-CD71+ early erythroid cells* ++++
BM-CD105+ endothelial cells* +++
BM-CD33+ myeloid cells* ++++
PB-CD56+ NK cells* ++++
PB-BDCA4+ dendritic cells* +++
PB-CD14+ monocytes* ++++
PB-CD19+ B cells* ++++
B lymphoblasts* ++++
CD4+ T cells* +++
CD8+ T cells* +++
  1. The median (med) was calculated based on expression of TRIP-Br2 across all human tissues; med × 3: 3-fold more than the median; med × 10: 10-fold more than the median. In silico TRIP-Br2 expression, (χ), across all human tissues was scored via the following scheme: +: (χ) ≤ median; ++: median < (χ) ≤ med × 3, +++: med × 3 <(χ) ≤ med × 10, ++++: med × 10 <(χ). TRIP-Br2 is found to be highly expressed in human tissues such as bone marrow, thymus, tonsil and smooth muscle. TRIP-Br2 is also highly expressed in the highly proliferative lymphohematopoietic cell lineages. *Denotes high TRIP-Br2 expression in these cells and tissues. BM: Bone marrow-derived; PB: Peripheral blood-derived.