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Table 1 Baseline characteristics of treated patients.

From: Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma

ID Number

Gender

Age (years)

KPS (%)

HLA-A2

LDH

Stage IV

Sites of Metastasis

Prior Cytokine Therapy

Prior Chemotherapy

0001–1103

M

49

80

+

169

M1b

Abdominal wall, thorax

IL2

Yes

0002–2101

M

30

90

+

130

M1b

Lung

IL2

No

0002–2102

F

39

80

+

429

M1c

Skin, lymph nodes, liver

IFNα2b

Yes

0003–3101

M

44

90

-

575

M1c

Skin, lymph nodes, lung

IL2 and IFNα2b

Yes

0003–3102

M

67

80

+

1388

M1c

Lymph nodes, skin, lung, liver

IL2 and IFNα2b

Yes

0004–4101

M

40

100

+

132

M1a

Skin

IFNα2b

No

0004–4102

M

36

90

+

333

M1c

Lymph nodes, spleen, liver

IFNα2b

Yes

0004–4103

F

54

90

-

94

M1c

Skin, liver

IFNα2b

No

0004–4104

M

76

90

-

282

M1c

Skin, lung

IFNα2b

No

  1. ID = identification. KPS = Karnofsky performance status. LDH = lactate dehydrogenase (on Day 1 of Cycle 1). M = male. F = female. IFN = interferon. IL2 = interleukin-2.