Figure 4

ROC curve analysis showing sensitivity and specificity of Hum FFPET 44 k and Human 44 k microarrays with cRNA generated from FF and FFPET samples. The ROC curves demonstrated the sensitivity and specificity of microarray hybridizations with cRNAs from FF samples on Hum FFPET 44 k v2.0 (solid red line) and Human 44 k v1.0 (solid blue line) and cRNAs from FFPET samples on Hum FFPET 44 k v2.0 (dashed red line) and Human 44 k v1.0 (dashed blue line). The number of false positives on the x-axis indicated the specificity (data derived from liver versus liver arrays); the number of positive on the y-axis indicated the sensitivity (data derived from liver versus muscle experiments). Each ROC curve was generated with data from one pair of liver versus liver arrays against data from one pair of liver versus liver arrays, and one representative ROC curve of three plots was shown for each method.