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Table 4 Levels of tumor markers in plasma of breast cancer patients and healthy controls.

From: Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer

Group n Median Mean S.D. Lower-upper quartile p-value
CEA (ng/ml)
healthy controls 58 1.13 1.62 1.46 0.84 – 1.75 0.04
cancer patients 37 1.54 2.45 3.11 1.00 – 2.11  
CA15-3 (U/ml)
healthy controls 58 12.3 13.28 5.45 9.5 – 16.4 0.63
cancer patients 37 14.0 13.74 5.79 8.3 – 18.5  
CYFRA 21.1 (ng/ml)
healthy controls 58 0.41 0.53 0.48 0.24 – 0.60 0.06
cancer patients 37 0.54 0.63 0.44 0.35 – 0.75  
Leptin (ng/ml)
healthy controls 58 27.70 33.51 23.01 17.80 – 41.80 0.05
cancer patients 37 23.01 24.19 16.09 10.02 – 31.11  
Osteopontin (ng/ml)
healthy controls 50 45.90 47.13 11.9 38.70 – 52.20 0.0003
cancer patients 73 54.73 59.47 15.37 47.13 – 66.98  
  1. Shown are median, mean and S.D. values, as well as lower and upper quartiles. The p-values are for differences between patients and healthy controls measured by the Kruskal-Wallis test.