Table 3 Comparison of serum proteome patterns among different sub-groups of breast cancer patients.
Component m/z value | S.D. | p-value | Frequency [%] |
|---|---|---|---|
Age (median = 56.5 years) | >median (n = 42) vs. <median (n = 42) | ||
5353.64 | 11.54 | 0.020 | 48.4 |
2475.96 | 2.37 | 0.029 | 19.9 |
4098.35 | 25.90 | 0.032 | 22.5 |
3024.45 | 11.71 | 0.035 | 20.2 |
4070.43 | 5.58 | 0.048 | 19.2 |
T – primary tumor size | T1 (n = 44)vs. T2 (n = 40) | ||
5353.64 | 11.54 | 0.033 | 21.9 |
2873.93 | 7.13 | 0.038 | 20.5 |
5343.98 | 6.26 | 0.051 | 15.8 |
3024.45 | 11.71 | 0.073 | 32.8 |
3249.64 | 5.24 | 0.075 | 12.4 |
N – nodal status | N0 (n = 63)vs. N1 (n = 20) | ||
8618.25 | 10.83 | 0.024 | 45.1 |
8602.25 | 29.35 | 0.036 | 29.5 |
2909.04 | 10.58 | 0.038 | 32.5 |
8607.98 | 5.60 | 0.040 | 25.7 |
8682.92 | 8.83 | 0.047 | 28.2 |
G – histopathological grade | G1+G2 (n = 54)vs. G3 (n = 20) | ||
2937.50 | 6.76 | 0.004 | 34.1 |
2556.63 | 8.07 | 0.007 | 44.1 |
2909.04 | 10.58 | 0.011 | 36.8 |
7547.58 | 12.44 | 0.022 | 37.7 |
4793.63 | 5.91 | 0.026 | 8.1 |
ER – estrogen receptor status | ER(-) (n = 29) vs. ER(+) (n = 51) | ||
7915.93 | 29.15 | 0.038 | 42.4 |
6302.67 | 4.03 | 0.039 | 23.6 |
8246.58 | 14.13 | 0.043 | 27.5 |
2599.96 | 3.93 | 0.044 | 28.9 |
3367.65 | 13.43 | 0.061 | 22.4 |
PR – progesterone receptor status | ER(-) (n = 32) vs. ER(+) (n = 49) | ||
7101.57 | 8.39 | 0.002 | 50.7 |
9965.62 | 16.77 | 0.014 | 37.3 |
7750.49 | 24.72 | 0.015 | 30.6 |
3367.65 | 13.43 | 0.018 | 30.5 |
9934.38 | 23.21 | 0.020 | 28.3 |